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NSW Curriculum
NSW Education Standards Authority

11–12Biology 11–12 Syllabus (2025)

Record of changes
Implementation from 2027
Expand for detailed implementation advice

Content

Year 12

Diseases

Relevant Working scientifically outcomes and content must be integrated with each focus area. All the Working scientifically outcomes and content must be addressed by the end of Year 12.

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Non-infectious diseases
  • Use examples to explain the impact of genetics, environment and nutrition on the development of non-infectious diseases in humans

  • Compare the causes and effects of a range of non-infectious diseases in humans

  • Explain the Aboriginal Cultural Practices of using native grasses to prevent nutritional disease

  • Conduct a secondary-source investigation to evaluate the effectiveness of a campaign to prevent a non-infectious disease

Infectious diseases
  • Use examples of infectious diseases to classify infectious agents as macroorganisms, microorganisms or non-cellular pathogens

  • Describe the adaptive features of prions, viruses, bacteria, protozoans, fungi and macroparasites

  • Compare direct contact, indirect contact and vector transmission of pathogens that facilitate entry into and transmission between hosts

  • Conduct a laboratory experiment to assess the effect of antimicrobial treatment on the growth of microorganisms found in food or water

  • Distinguish between innate and adaptive immune response

  • Interpret and construct diagrams of the innate immune system including barriers, secretions, phagocytic leukocytes, antimicrobial proteins, inflammatory response and fever

  • Conduct a scientific investigation to determine the effect of temperature on the viability of a non pathogenic E. coli

  • Discuss the role of interleukin communication between innate and adaptive cells

  • Describe the roles of helper T cells, cytotoxic T cells, memory T cells and suppressor T cells of the cell-mediated immune response within the adaptive immune system

  • Describe the roles of plasma cells, memory B cells and antibodies of the humoral immune response within the adaptive immune system

  • Interpret and construct diagrams of the adaptive immune system to demonstrate how the cell-mediated and humoral components of the immune system respond after primary and secondary exposure to a pathogen

  • Distinguish between passive and active immunity

  • Use data to demonstrate how vaccinations support adaptive immunity

  • Compare pharmaceutical treatments for viral and bacterial diseases

  • Describe the use of an Aboriginal bush medicine in treating disease

  • Explain procedures that can be employed to limit transmission of infectious diseases in humans

Epidemiological studies
  • Explain the role of epidemiology in public health and disease control

  • Compare the features of observational, analytical and experimental epidemiological studies

  • Discuss the features of randomised clinical trials, cross-sectional studies, case studies and cohort studies

  • Assess surveillance methods used in the management of disease

  • Distinguish between incidence, prevalence, morbidity and mortality as used in epidemiological studies

  • Analyse data of the incidence, prevalence, morbidity and mortality rates for a non-infectious and an infectious disease in humans

  • Explain how epidemiological information is used to create strategies that prevent and treat a selected disease in humans

  • Outline the impact of the work of selected scientists on current disease management

  • Distinguish between causal and correlational relationships

  • Interpret evidence from secondary sources about herpes, human papillomavirus (HPV) and cervical cancer to discuss scientific causation and correlation

  • Analyse data that demonstrates a causal relationship for a selected environmental disease

  • Assess approaches taken to reduce selection error and confounding factors in an epidemiological study

  • Interpret data and information to outline causes of error, information bias, measurement bias and limitations in data relating to a disease during an epidemic or pandemic

  • Evaluate, using examples, the benefits of engaging in an epidemiological study on preventing and managing disease

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